Table 2.
Selected families of transcription factors detected in the mid-foregut.
| Average Signal | Average Signal | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Gene | Affymetrix I | 16–20s | 21–25s | 26–30s | Gene | Affymetrix | 16–20s | 21–25s | 26–30s |
|
Fox family
|
Gata family
|
||||||||
| Foxa1 | 1418496_at | 2093 | 2252 | 2844 | Gata1 | 1449232_at | 164 | 106 | 175 |
| Foxa2 | 1422833_at | 635 | 497 | 712 | Gata2 | 1450333_a_ | 477 | 577 | 510 |
| Foxc1 | 1419486_at | 411 | 565 | 503 | Gata4 | 1418863_at | 288 | 323 | 330 |
| Foxd1 | 1418876_at | 355 | 471 | 460 | Gata5 | 1450125_at | 149 | 147 | 172 |
| Foxf2 | 1418220_at | 56 | 109 | 113 t | Gata5 | 1450126_at | 452 | 444 | 448 |
| Foxg1 | 1418357_at | 193 | 331 | 394 | Gata6 | 1425463_at | 101 | 99 | 89 |
| Foxj2 | 1420374_at | 166 | 130 | 174 | Gata6 | 1425464_at | 548 | 580 | 498 |
| Foxk2 | 1428354_at | 374 | 857 | 527 | |||||
| Foxm1 | 1448833_at | 374 | 639 | 473 t |
Hox family
|
||||
| Foxm1 | 1417748_x_ | 231 | 235 | 253 | Hoxa1 | 1420565_at | 4171 | 2838 | 2510 a |
| Foxo1 | 1416983_s_ | 349 | 561 | 540 | Hoxa2 | 1419602_at | 188 | 256 | 224 |
| Foxp1 | 1421141_a_ | 98 | 81 | 139 | Hoxa3 | 1427433_s_ | 100 | 175 | 149 |
| Foxp1 | 1421142_s_ | 218 | 183 | 301 | Hoxa4 | 1427354_at | 42 | 80 | 172 a,t |
| Foxp1 | 1421140_a_ | 120 | 205 | 131 | Hoxa4 | 1420227_at | 90 | 85 | 125 |
| Foxp1 | 1435222_at | 522 | 556 | 1545 a,t | Hoxa5 | 1448926_at | 103 | 149 | 259 t |
| Foxp1 | 1435221_at | 1733 | 2116 | 2561 a,t | Hoxb1 | 1453501_at | 539 | 809 | 493 |
| Foxp3 | 1455805_x_ | 341 | 340 | 363 | Hoxb2 | 1449397_at | 799 | 928 | 801 |
| Hoxb4 | 1460379_at | 395 | 408 | 364 | |||||
|
Tbx family
|
Hoxb5 | 1418415_at | 421 | 512 | 517 | ||||
| Tbx1 | 1425779_a_ | 391 | 373 | 251 | Hoxb7/b8 | 1452493_s_ | 81 | 120 | 186 a |
| Tbx2 | 1422545_at | 177 | 232 | 278 | Hoxc4 | 1422870_at | 351 | 620 | 608 |
| Tbx3 | 1448029_at | 491 | 564 | 503 | |||||
| Tbx6 | 1449868_at | 84 | 100 | 76 | |||||
| Tbx20 | 1425158_at | 96 | 101 | 83 | |||||
t= Student’s t-test p ≤ 0.05
a= ANOVA p ≤ 0.05
The table includes the average signal for genes detected in the mid-foregut and lung regions (detection p ≤ 0.05) at 16–20s, 21–25s and 26–30s developmental stages. Only genes with a signal ≥ 100 at any stage are listed. Most genes do not change the level of expression as the lung buds. A few of them change the level of expression significantly indicated by Student’s t and/or ANOVA tests.