Table 5.
The Effects of the Inhibitors on the Thermal Stability of GDHa
| compound | rate (min−1) | R2 | half-life (min) | temp (°C) |
|---|---|---|---|---|
| no drug | 0.020 (0.001) | 0.99 | 34.5 | 50 |
| bithionol | 0.048 (0.002) | 0.99 | 14.4 | 50 |
| diethystilbestrol | 0.202 (0.017) | 0.98 | 3.4 | 50 |
| palmitoyl CoA | 0.169 (0.011) | 0.99 | 4.1 | 50 |
| CK2 inhibitor | 0.048 (0.003) | 0.98 | 14.4 | 50 |
| GW5074 | 0.084 (0.016) | 0.87 | 8.2 | 50 |
| BH3I-2 | 0.046 (0.006) | 0.90 | 15.0 | 50 |
| calmidazolium | 0.017 (0.031) | 0.82 | 40.6 | 50 |
| no drug | 0.127 (0.019) | 0.93 | 5.4 | 54 |
| hexachlorophene | 0.113 (0.007) | 0.98 | 6.1 | 54 |
| ATA | 0.028 (0.002) | 0.94 | 24.6 | 54 |