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. 2008 Jul 2;3(7):e2580. doi: 10.1371/journal.pone.0002580

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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HIV replication in selected cell lines expressing various GBV-C NS5A peptides summarized in Fig. 1 was assessed by monitoring HIV p24 antigen release into culture supernatants. FS = the 126–237 frame-shift construct (see methods). Numbers refer to the NS5A amino acid sequence expressed in each cell line. * = HIV replication curves significantly less HIV p24 antigen than the frame shift control. (P<0.01 for the three cell lines that included amino acids 152–165 on days 3, 4, 5).