Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 Jul 2;3(7):e2580. doi: 10.1371/journal.pone.0002580

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

PMC Copyright notice

MT-2 cells were incubated with three concentrations (10, 25, and 50 µg/ml) of synthetic peptides containing GBV-C S158E (A) or 152–167scr (B) amino acid sequences in which an N-terminal Tat-protein transduction domain was included, and the peptides were conjugated to FITC. Cells were washed one hour later and FITC was monitored by flow cytometry. Cells were infected with HIV 24 hrs after incubation, and dose related inhibition of HIV replication was observed for the S158E peptide, but not the 152–167scr peptide compared to the no peptide control (NP). * HIV p24 antigen area under the curve was less than controls (p<0.01).