Table 2.
Associations between CAR overexpression and clinicopathological characteristics of the 23 CAR positive endometrial adenocarcinoma cases
Clinicopathological characteristics | CAR expression | ||
< 31% (%) | ≥31% (%) | P-value | |
Patients | 15 (65) | 8 (35) | |
Age (mean± SD), years | 62.9 ± 12.1 | 61.5 ± 9.6 | 0.469 |
< 63 | 8 (35) | 5 (22) | |
≥63 | 7 (30) | 3 (13) | |
pStage (FIGO) | 0.147 | ||
I | 12 (52) | 6 (27) | |
II | 3 (13) | 0 (0) | |
III | 0 (0) | 1 (4) | |
IV | 0 (0) | 1 (4) | |
Histological type | 0.181 | ||
Positive for squamous elements | 2 (9) | 3 (13) | |
Negative for squamous elements | 13 (56) | 5 (22) | |
Histological grade | 0.379 | ||
Well differentiated | 3 (13) | 0 (0) | |
Moderately differentiated | 11 (48) | 7 (31) | |
Poorly differentiated | 1 (4) | 1 (4) | |
Ki-67 protein statement | 0.057 | ||
Ki-67 below mean (<40%) | 10 (43) | 2 (8) | |
Ki-67 over mean (≥ 40%) | 5 (22) | 6 (27) |