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. 2007 Jun 14;362(1484):1445–1457. doi: 10.1098/rstb.2007.2127

Figure 3.

Figure 3

Mechanotransduction differences between valvular and vascular endothelial cells. Valvular endothelial cells align perpendicular to flow independent of PI-3 kinase, which is required for vascular endothelial cell alignment. Alignment of both endothelial cells is dependent on focal adhesion rearrangement. Modified from Butcher et al. (2004).