Table 2. AQP5 expression level and CML Patient information.
patient | AQP5 expression | bcr-abl amplification | bcr-abl mutation | secondary chromosomal change* | ||||
Pre R | Post R | Pre R | Post R | Pre R | Post R | Pre R | Post R | |
A | − | − | − | + | − | + | − | + |
B | − | ++ | − | − | − | + | − | + |
C | ++ | ++ | − | − | − | + | + | + |
D | − | − | − | − | − | − | + | − |
E | − | + | − | − | − | − | − | − |
F | − | + | − | − | − | + | − | + |
G | − | − | − | − | − | + | − | − |
H | − | − | − | − | − | − | − | + |
I | + | ++ | − | − | − | − | − | − |
Secondary chromosomal change denotes abnormal changes detected from conventional karyotyping test other than bcr-abl amplification; t(9,22).
preR and postR denote AQP5 expression level, or the existence of bcr-abl amplification, mutation, or secondary chromosomal change before and after the emergence of imatinib mesylate resistance, respectively.