FIGURE 8.

Auranofin effect on E. granulosus larval worms. Protoscoleces were incubated in vitro at 37 °C, 5% CO₂ in DMEM with 10 μm auranofin, a TGR inhibitor, or its vehicle (DMSO) as a control. A, control protoscoleces after 30 h of culture. B, treated protoscoleces after 12 h of culture (all protoscoleces were dead, note the disorganization of the parenchyma and the loss of the hooks or the entire crown of hooks). C, treated protoscoleces after 30 h of culture. The scale bar on C corresponds to 100 μm.