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HO enzymatic activity is increased in response to Mtb infection. Biliverdin is a precise indicator of the amount of released CO (see “Results” for details). HO enzymatic activity was measured in RAW 264.7 (A), RAW 264.7 γ-NO(-) (B), and RAW 264.7 (C) cells with 1400W 24 h post-infection with Mtb. U, uninfected; I, infected. Results are expressed as mean ± S.E.*, p <0.001 (n = 3–6/gp).
