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Detection of CD4+ cells and loss of insulin staining in infiltrated islets from DR4/164/Rag2o/o mice. Immunofluorescence staining for insulin (blue) and CD4 (green) in an infiltrated islet from a 28 week old female DR4/164/Rag2o/o mouse (A). Immunohistochemistry staining for insulin (brown) in infiltrated islets from a female DR4/164/Rag2o/o mouse (B).
