Table 5.
Risk of death and myocardial infarction in relation to the quartiles of heart rate recovery 3 minutes after exercise
| 7-year Follow-up | |||
|---|---|---|---|
| Events, n (%) | HR (95% CI)1 | HR (95% CI) 2 | |
| Sudden Death | |||
| I (< 50) | 43 (1.4%) | 1.00 (reference) | 1.00 (reference) |
| II (50–57) | 47 (1.4%) | 1.02 (0.67 – 1.54) | 1.24 (0.81 – 1.90) |
| III (58–65) | 20 (0.7%) | 0.50 (0.29 – 0.85) | 0.65 (0.37 – 1.14) |
| IV (>65) | 28 (0.9%) | 0.73 (0.45 – 1.18) | 1.10 (0.65 – 1.85) |
| Beta (P-value)3 | −.017 (0.009) | −.006 (0.41) | |
| Fatal/NF MI | |||
| I (< 50) | 223 (7.5%) | 1.00 (reference) | 1.00 (reference) |
| II (50–57) | 219 (6.7%) | 0.90 (0.75 – 1.09) | 0.96 (0.79 – 1.16) |
| III (58–65) | 177 (5.9%) | 0.83 (0.68 – 1.01) | 0.94 (0.77 – 1.16) |
| IV (>65) | 150 (5.1%) | 0.73 (0.59 – 0.89) | 0.90 (0.72 – 1.13) |
| Beta (P-value)3 | −.008 (0.003) | −.002 (0.57) | |
| 25-year Follow-up | |||
| CHD Death | |||
| I (< 50) | 396 (13.3%) | 1.00 (reference) | 1.00 (reference) |
| II (50–57) | 439 (13.4%) | 1.00 (0.88 – 1.15) | 1.11 (0.96 – 1.27) |
| III (58–65) | 341 (11.4%) | 0.88 (0.76 – 1.01) | 1.05 (0.90 – 1.22) |
| IV (>65) | 297 (10.0%) | 0.79 (0.68 – 0.92) | 1.03 (0.87 – 1.21) |
| Beta (P-value)3 | −.007 (0.001) | 0.000 (0.87) | |
| Death All-causes | |||
| I (< 50) | 1272 (42.8%) | 1.00 (reference) | 1.00 (reference) |
| II (50–57) | 1238 (37.7%) | 0.88 (0.81 – 0.95) | 0.95 (0.88 – 1.03) |
| III (58–65) | 969 (32.5%) | 0.78 (0.71 – 0.84) | 0.91 (0.83 – 0.99) |
| IV (>65) | 889 (30.1%) | 0.73 (0.67 – 0.80) | 0.90 (0.82 – 0.99) |
| Beta (P-value)3 | −.008 (0.000) | −.003 (0.04) | |
Abbreviations: CHD: coronary heart disease; HR: Hazard ratio estimated from Cox-regression MI: myocardial infarction
1
Univariate analyses (age stratification only)
2
Multivariate analyses adjusted for age, cigarettes smoked per day, systolic blood pressure, low density lipoprotein, high density lipoprotein, triglycerides, body mass index, fasting glucose, race, parental history of CHD and exercise duration.
3
From model using heart rate as a continuous variable
All analyses were stratified by age categories