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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Neurochem Int. 2007 Nov 26;52(6):1068–1075. doi: 10.1016/j.neuint.2007.11.006

Figure 5.

Figure 5

The figure demonstrates the bladder contraction frequency (i.e. BCF) measured during in vivo cystometrographic experiments in spinal cord injured rats (n=6) before (i.e. day 0) and after (i.e. day 2) bladder injection with BoNT-A. Voiding and non-voiding bladder contractions were distinguished by measuring whether urine was expelled during each contraction. The frequency of bladder contractions per hour were categorized as “non-voiding bladder contractions” (i.e. BCF-NV) and as “voiding bladder contractions” (i.e. BCF-V). While BoNT-A had no effect on the frequency of voiding bladder contractions, it significantly inhibited bladder contraction frequency of non-voiding bladder contractions (i.e. BCF-NV). *denotes p<0.05 between day 0 and day 2 groups using the two-tailed student t-test.