Figure 3.

Alignment of the amino acid sequence of LLAE0048C, from L. laeta venom glands, with known hyaluronidases. Residues are numbered according to the aligned hyaluronidases sequences and dots represent gaps introduced to improve alignment. The conserved cystein residues are indicated by asterisks. Black and gray indicate amino acids that are identical or conserved, respectively. The three key catalytic residues are represented by arrows. The abbreviation and GenBank accession number for the hyaluronidases sequences aligned are: hyaluron1, Bos taurus hyaluronidase (AAP55713); hyaluron2, Apis mellifera hyaluronidase (AAA27730) and hyaluron3, Vespula germanica hyaluronidase (CAL59818).