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. 2008 Jul 9;3(7):e2637. doi: 10.1371/journal.pone.0002637

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Chen et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) and (B) The expression levels of CD133, CD117 (c-Kit), and ABCG2 were analyzed by FACS assay in LC-CD133⁺ and LC-CD133⁻. The capabilities of (C) the migration/invasion and (D) the tumor foci (soft agar colony) formation in LC-CD133⁺ were significantly increased compared with LC-CD133⁻ (*p<0.001). Data shown here are the mean±SD of three experiments.