Table 1. Marker evaluation pipeline: cases and controls.
Patient Class | Filtering Set | Mini-Triage Set | Triage Set | Overlapa |
Ovarian Cancer Cases | 50 | 35 | 71 | 17 |
Healthy Controlsb | 9 | 12 | 58 | 12 |
Surgical Benignsc | 0 | 16 | 53 | 16 |
Surgical Normalsd | 0 | 8 | 32 | 8 |
Total | 59 | 71 | 214 |
Overlapping specimens in the Mini-Triage and Triage sets
Healthy Controls: women enrolled in prospective screening trials who remained free of ovarian cancer for at least two years after serum collection.
Surgical Benigns: women with surgically confirmed benign ovarian pathology.
Surgical Normals: women that underwent surgery but no ovarian pathology was identified.