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. 2008 Jul 18;4(7):e1000122. doi: 10.1371/journal.pcbi.1000122

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Ramakrishnan, Bhalla.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Number of nonautocatalytic configurations as a function of number of reactions. (B) Percentage of bistable configurations for 3, 4, and 5 molecules as a function of number of reactions. Same symbols as in (A). (C) Comparison of bistability percentage for entire dataset (x axis) and set without autocatalysis (y axis). The thick line indicates equal percentages. 3-molecule systems have fewer bistables without autocatalysis, but 4 and 5 molecule systems have nearly equal bistables if autocatalytic reactions are excluded. The different points on each plot are for numbers of reactions. As bistability declines for large reaction numbers for 3 molecules, this curve folds back on itself.