Figure 2.

Effects of salicylates and acetaminophen on neutrophil Erk activity. Neutrophils were incubated for 10 min at 37°C in the absence or presence of aspirin (ASA; □), NaS (○), or acetaminophen (▵), followed by stimulation for 2 min with 100 nM FMLP (A) or 20 μM AA (B), or for 10 min with 1 μg/ml PMA (C), and determination of Erk activity. Results are expressed as percent of stimulated Erk activity in the absence of inhibitors, and are the mean ± SEM of three experiments.