Table 1.
Characteristics of patients aged 35-74 in derivation and validation cohorts in QRESEARCH database (version 19) 1993-2008
| Derivation cohort | Validation cohort | ||||
|---|---|---|---|---|---|
| No (%) of women | No (%) of men | No (%) of women | No (%) of men | ||
| No of patients | 773 291 | 762 292 | 375 763 | 374 469 | |
| Total person years observation | 5 645 104 | 5 280 571 | 2 594 842 | 2 470 729 | |
| Median age (IQR) | 49 (41-60) | 48 (40-58) | 49 (41-59) | 47 (40-57) | |
| Ethnicity: | |||||
| White or not recorded | 752 241 (97.3) | 743 159 (97.5) | 363 516 (96.7) | 363 097 (97.0) | |
| Indian | 3635 (0.47) | 3693 (0.48) | 2241 (0.60) | 2200 (0.59) | |
| Pakistani | 2035 (0.26) | 2033 (0.27) | 1114 (0.30) | 1246 (0.33) | |
| Bangladeshi | 1213 (0.26) | 1269 (0.17) | 611 (0.16) | 723 (0.19) | |
| Other Asian | 1802 (0.16) | 1422 (0.19) | 1086 (0.29) | 988 (0.26) | |
| Black Caribbean | 3928 (0.51) | 3109 (0.41) | 1870 (0.50) | 1495 (0.40) | |
| Black African | 3655 (0.47) | 3316 (0.44) | 2423 (0.64) | 2201 (0.59) | |
| Chinese | 1128 (0.15) | 859 (0.11) | 675 (0.18) | 478 (0.13) | |
| Other including mixed | 3654 (0.47) | 3432 (0.45) | 2227 (0.59) | 2041 (0.55) | |
| Risk factors: | |||||
| Ethnicity recorded | 209 214 (27.1) | 181 110 (23.8) | 108 540 (28.9) | 94 522 (25.2) | |
| BMI recorded | 622 741(80.5) | 562 278 (73.8) | 304 084 (80.9) | 274 403 (73.3) | |
| Smoking recorded | 703 574 (91.0) | 650 460 (85.3) | 344 194 (91.6) | 319 800 (85.4) | |
| Cholesterol/HDL ratio recorded | 265 402 (34.3) | 247 116 (32.4) | 210 638 (56.1) | 125 037 (33.4) | |
| Systolic blood pressure recorded | 711 935 (92.1) | 647 782 (85.0) | 344 967 (91.8) | 313 125 (83.6) | |
| Complete BMI and smoking | 615 301 (79.6) | 554 070 (72.7) | 301 016 (80.1) | 270 956 (72.4) | |
| Positive family history of CHD | 97 448 (12.6) | 73 740 (9.7) | 48 610 (12.9) | 36 761 (9.8) | |
| Current smoker | 176 202 (22.8) | 208 913 (27.4) | 88 672 (23.6) | 104 829 (28.0) | |
| Treated hypertension | 55 069 (7.12) | 42 607 (5.59) | 25 953 (6.91) | 20 083 (5.36) | |
| Type 2 diabetes | 13 127 (1.70) | 17 107 (2.24) | 6186 (1.65) | 8179 (2.18) | |
| Rheumatoid arthritis | 7187 (0.93) | 2996 (0.39) | 3310 (0.88) | 1380 (0.37) | |
| Atrial fibrillation | 2692 (0.35) | 1880 (0.25) | 1242 (0.33) | 2155 (0.58) | |
| Chronic kidney disease | 1227 (0.16) | 1117 (0.15) | 621 (0.17) | 498 (0.13) | |
IQR=interquartile range; BMI=body mass index; HDL=high density lipoprotein cholesterol; CHD=coronary heart disease.