Table 6.
Validation statistics for new QRISK2 model compared with modified NICE equation in validation cohort. Figures are means (95% confidence intervals)
| QRISK2 model | QRISK1 model | Modified Framingham equation | |
|---|---|---|---|
| Women | |||
| R2 | 43.47 (42.78 to 44.16) | 42.94 (42.23 to 43.66) | 38.87 (38.12 to 39.62) |
| D statistic | 1.795 (1.769 to 1.820) | 1.776 (1.750 to 1.801) | 1.632 (1.606 to 1.658) |
| ROC statistic | 0.817 (0.814 to 0.820) | 0.814 (0.811 to 0.817) | 0.800 (0.797 to 0.803) |
| Brier score | 0.086 (0.083 to 0.089) | 0.081 (0.078 to 0.084) | 0.093 (0.090 to 0.096) |
| Men | |||
| R2 | 38.38 (37.75 to 39.01) | 37.63 (36.99 to 38.27) | 34.78 (34.12 to 35.45) |
| D statistic | 1.615 (1.594 to 1.637) | 1.590 (1.568 to 1.612) | 1.495 (1.473 to 1.517) |
| ROC statistic | 0.792 (0.789 to 0.794) | 0.788 (0.786 to 0.791) | 0.779 (0.776 to 0.782) |
| Brier score | 0.136 (0.134 to 0.139) | 0.128 (0.125 to 0.131) | 0.177 (0.174 to 0.180) |