Table 1.

Number of patients with acute hepatitis E and healthy negative controls showing significant proliferation of peripheral blood mononuclear cells with various pools of peptides corresponding to hepatitis E virus open reading frames (ORF)2 and ORF3 proteins

ORF	Peptide pool	Amino acid region of the protein	Patients (n = 40)	Healthy controls (n = 21)	P-value*
ORF2	Pool 1	1–84	9	1	ns
	Pool 2	73–156	14	0	0.005
	Pool 3	145–228	9	1	ns
	Pool 4	217–300	12	2	ns
	Pool 5	289–372	15	1	0.02
	Pool 6	361–444	17	1	0.01
	Pool 7	433–516	5	2	ns
	Pool 8	505–588	12	0	0.01
	Pool 9	577–660	14	3	ns
ORF3	Pool 10	1–68	8	2	ns
	Pool 11	49–123	7	0	ns

^*Patients vs controls using chi-square test (with Yates’ correction, where applicable).