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. 2008 Jul 9;3(7):e2642. doi: 10.1371/journal.pone.0002642

Table 2. Characteristics of the force-pCa relationships in skinned papillary muscle fibers.

pCa50 Hill Coefficient Maximal Force (mN mm−2) pCa50 Hill Coefficient Maximal Force (mN mm−2)
Sarcomere Length 1.9 µm 1.9 µm 1.9 µm 2.3 µm 2.3 µm 2.3 µm
Tnnt2 +/−/TGWT (n = 10) 5.58±0.03 6.54±0.89 45.9±4.6 5.71±0.03 3.65±0.11 62.3±6.5
Tnnt2 +/−/TGK210Δ (n = 7) 5.34±0.08 9.34±2.47 34.5±5.3 5.46±0.04 6.72±1.09 63.1±10.9
p <0.01 NS NS <0.01 NS NS

pCa50, pCa required for generation of 50% of maximal force. n, number of skinned fibers studied, taken from a total of 6 hearts in each group. NS, not significant. Data: mean±SE. p values correspond to the comparison between Tnnt2 +/−/TGWT and Tnnt2 +/−/TGK210Δ fibers at the same sarcomere length.