Table 1.
Force generation to 1 μM serotonin (5-HT) was not significantly altered by organ culture with the CoCl2 and CoPP inducers of HO-1 or organ culture (24 hrs) or acute treatment of organ cultured arteries with the HO-1 inhibitor 30 μM CrMP. (n =5–14)
| Condition | Force Generation (g) |
|---|---|
| Control | 8.3±1.0 |
| CrMP (acute) | 7.5±1.5 |
| CrMP (24 hrs) | 7.4±1.2 |
| Hemin (24 hrs) | 9.7±2.0 |
| CoCl2 | 8.5±1.2 |
| CoPP | 6.9±1.4 |
| CoCl2+CrMP (acute) | 9.9±2.2 |
| CoPP+CrMP (acute) | 11.3±1.9 |
| CoCl2+CrMP (24 hrs) | 11.1±1.6 |
| CoPP+CrMP (24 hrs) | 6.4±0.8 |
| CoCl2+Hemin (24 hrs) | 7.1±1.8 |