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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Neurochem Int. 2007 May 17;52(4-5):611–620. doi: 10.1016/j.neuint.2007.05.003

Figure 1.

Figure 1

Simplified diagrams of sex steroid synthesis. a) Steroids are in bold; enzymes are in italics. Steroids: pregnenolone=PREG; progesterone=PROG; dehydroepiandrosterone=DHEA; androstenedione=AE; testosterone=T; estrone=E1; estradiol=E2. Enzymes: cytochrome P450 side-chain cleavage=CYP11A1; cytochrome P450 17α-hydroxylase/C17,20 lyase=CYP17; 3β-hydroxysteroid dehydrogenase/isomerase=3β-HSD; 17β-hydroxysteroid dehydrogenase=17β-HSD; aromatase=CYP19; b) 3β-HSD catalyzes the oxidation and isomerization of DHEA into AE.