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. 2008 May 22;3:11. doi: 10.1186/1750-2187-3-11

Figure 4.

Figure 4

Signaling network topology for RANTES based on the top ten signaling metrics. The kinases JNK and ERK1/2 were found to play an important role in regulating RANTES from the PLS analysis. Legends shown in the top row were identified directly from the data (i.e. not a model output) as the top activators of either JNK or ERK1/2. Also see Table 3.