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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Biol Psychiatry. 2007 Sep 6;63(5):449–457. doi: 10.1016/j.biopsych.2007.06.005

Fig. 1.

Fig. 1

Most significant AKT1 SNP haplotypes associated with schizophrenia to date. Exon locations of the 3 main alternative AKT1 transcripts are shown at the top (http://genome.ucsc.edu/, human genome build 35). SNPs are positioned underneath with intervening distances in kilobases. Numbers 1–8 refer to SNPs typed in our study. The p values of the most significant haplotypes are given for each report of association between AKT1 and schizophrenia. The arrows depict over-representation (up arrow) or under-representation (down arrow) in cases. SNP alleles highlighted in bold are significantly associated with schizophrenia as single SNPs. Marker order and haplotypes are given in the reverse order here to that in the text, in accordance with the orientation of the gene on the UCSC genome browser.