Table 1.

Position and allele frequencies of AKT1 SNPs used in this study

SNP number	SNP name	Position (bp)*	AKT1 gene location #	Distance (bp)	Major allele	Minor allele	Minor allele frequency in ISHDSF
1	rs1130214	104,330,779	5’ UTR	2015	G	T	0.31
2	rs2494746	104,328,764	Intron 2	11312	G	C	0.08
3	rs3730358	104,317,452	Intron 3	6513	C	T	0.17
4+	rs2498799	104,310,939	Exon 9	702	G	A	0.25
5	rs2494732	104,310,237	Intron 11	46	A	G	0.45
6	rs3803304	104,310,191	Intron 11	4704	G	C	0.28
7	rs2498802	104,305,487	3’UTR	1347	C	G	0.34
8	rs2498804	104,304,140	3’UTR		G	T	0.34

^*University of California at Santa Cruz (UCSC) Human Genome Browser Gateway assembly May 2004

^#Based on AKT1 gene transcript variant 1 (NM_005163) which has 14 exons

⁺rs2498799 is a synonymous coding variant