Figure 3.

Gcn2 mediates an inhibition of translation initiation in response to different oxidants. (A) Polysome traces are shown for the wild-type and gcn2 mutant strain after treatments with oxidants as described for Figure 2A. Numbers in brackets are the p:m ratio. (B) Wild-type and gcn2 mutant cells were grown to exponential phase, treated with oxidants as described for Figure 2A, and protein synthesis measured as described for Figure 1A. Representative data are shown from repeat experiments.