Table VIII.
Summary of the concordance evaluations
| No compounds | Concordance % | Sensitivity % | Specificity % | |
| All compounds | 113 | 83.2 | 89.2 | 55.0 |
| Clastogensa | 71 | 87.3 | _ | _ |
| Aneugensb | 27 | 77.8 | _ | _ |
| Non-genotoxicc | 15 | 73.3 | _ | _ |
| German ring trial (7) | 20 | 85.0 | 92.9 | 66.7 |
| Miller et al. (9) | 54 | 83.3 | 95 | 76.5 |
| Japanese ring trial (11) | 62 | 82.3 | 91.5 | 53.3 |
| GUM Working group (10) | 27 | 88.9 | 100 | 25 |
| Kirkland et al. (12) | 125 | 80.8 | 87.0 | 56.0 |
Norfloxacin was negative in both assays whereas chloroaniline (not convincingly clastogenic), 2-chloro-4-nitroaniline, coumarin, dichloroacetic acid, 2-methyl-4-nitroaniline, N-(1-naphthyl)ethylenediamine2HCl, 4-nitroanthranilic acid, 4-nitro-o-phenylenediamine and phenacetin were negative in the in vitro MNT but positive in the in vitro CAT.
Carbendazim, carbon tetrachloride, chlordane, diazepam, nitrilotriacetic acid and oxazepam (all known as pure aneugenic compounds) were negative in the in vitro CAT but positive in the in vitro MNT.
Nafenopin was negative in the in vitro MN but positive in the in vitro CAT, l-ascorbic acid, n-butyl-N-(3-carboxypropyl)nitrosamine and triphenyltin hydroxide were positive in the in vitro MNT but negative in the in vitro CAT whereas only safrole was positive in both assays.