Table 8.
FKBP5 SNP Genotype-Dependent Correlations of CTQ Total Score and PSS Scores
CTQ Correlation With PSS Score Dependent on FKBP5 Genotype | Genotype | ||
---|---|---|---|
rs9296158 | |||
AA | AG | GG | |
No. of participants | 164 | 360 | 172 |
Pearson correlation R value | 0.470 | 0.374 | 0.169 |
Z values for difference | AA/AG = 1.17 | AG/GG = 2.35a | AA/GG = 3.00b |
rs1360780 | |||
CC | CT | TT | |
No. of participants | 238 | 347 | 125 |
Pearson correlation R value | 0.210 | 0.390 | 0.455 |
Z values for difference | CC/TT = 2.46a | CT/CC = 2.33a | TT/CT = 0.74 |
rs3800373 | |||
AA | AC | CC | |
No. of participants | 171 | 352 | 156 |
Pearson correlation R value | 0.248 | 0.350 | 0.435 |
Z values for difference | AA/CC = 2.59b | AC/AA = 2.30a | CC/AC = .83 |
rs9470080 | |||
CC | CT | TT | |
No. of participants | 222 | 336 | 135 |
Pearson correlation R value | 0.215 | 0.392 | 0.465 |
Z values for difference | CC/TT = 1.91 | CT/CC = 1.20 | TT/CT = 1.03 |
Abbreviations: CTQ, Childhood Trauma Questionnaire; PSS, PTSD Symptom Scale; PTSD, posttraumatic stress disorder; SNP, single-nucleotide polymorphism.
P < .05.
P < .01.