Skip to main content
. 2008 May 24;36(11):3847–3856. doi: 10.1093/nar/gkn310

Figure 4.

Figure 4.

Pol θ error rates compared to other DNA polymerases. (A) Single-base deletions (B) Single-base additions (C) Base substitutions. Family Y: hPol κ and hPol η error rates are taken from (20). Family X: hPol β and hPol λ error rates are taken from (57). Family B: hPol α error rates are unpublished results from Kokoska, R.J. and Kunkel, T.A., yPol δ (Exo–) error rates are taken from (58), yPol ɛ (Exo–) error rates are taken from (59) and yPol ζ error rates are taken from (50). Family A: hPol θ and hPol ν data are from this study. For hPol ν, at neutral pH, a mutation frequency of 2.6% was obtained (64 mutant plaques from a total of 6432). Of these, 22 clones were sequenced and as with the previous study (24), these clones show a preference for G to A base substitutions. hPol γ (Exo–) (+p140 and p55) error rates are from (23) and Kf (Exo−) error rates are taken from (21).