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Expression of known and putative STAT5 target genes in STAT5A and STAT5B double (A) and single (B) knockdown. RNAs were isolated from Ba/F3-β cells treated as described in Figure 1, and analyzed by RT-qPCR. Six distinct expression profiles could be recognized, represented here by selected genes (see also Table 2), revealing a clear differential contribution of STAT5A and STAT5B in regulating expression of STAT5 target genes.
