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. Author manuscript; available in PMC: 2008 Jun 30.
Published in final edited form as: Chem Biol. 2008 Jan;15(1):70–77. doi: 10.1016/j.chembiol.2007.12.010

Fig. 4. Activity of the principle hits in a cell culture model of Cryptosporidium infection.

Fig. 4

(A) Representative cytoxocity assay showing the cytolytic effects of compounds G and H monitored by the release of lactate dehydrogenase (LDH). (B) Parasite proliferation as measured by RT-PCR over 48 hours, the period over which the anti-parasitic effects of compounds A-K were determined. (C) VVL-ELISA C. parvum growth assay; (D) RT-PCR C. parvum growth assay. Assays as described in Materials and Methods.