TABLE 1.
Skin cooling-evoked changes in physiological variables
Before cooling | End of cooling | During rewarming | |
---|---|---|---|
BAT SNA (% of baseline) | 100 ± 26 | 760 ± 128*** | 96 ± 27††† |
TBAT (°C) | 35.5 ± 0.3 | 36.4 ± 0.3*** | 35.8 ± 0.4*, †† |
Expired CO2 (%) | 4.0 ± 0.1 | 4.4 ± 0.1*** | 4.0 ± 0.1††† |
HR (bpm) | 425 ± 17 | 474 ± 22*** | 408 ± 18††† |
MAP (mmHg) | 128 ± 5 | 131 ± 5 | 122 ± 5† |
Tskin (°C) | 38.1 ± 0.3 | 32.9 ± 0.5*** | 38.0 ± 0.7††† |
Trec (°C) | 37.3 ± 0.1 | 37.4 ± 0.1 | 37.3 ± 0.2†† |
Tbrain (°C) | 36.5 ± 0.1 | 36.7 ± 0.1** | 36.6 ± 0.2† |
The data represent the mean ± SEM (n = 6) of the physiological variables in the course of a skin cooling-rewarming challenge. Values before cooling were the averages during the 1-min period immediately prior to skin cooling. Values of end of cooling were those at the end of the skin cooling period (TBAT, expired CO2, HR, and Tskin) or the averages during the 1-min period immediately prior to the end of the skin cooling (BAT SNA, MAP, Trec, and Tbrain). Values during rewarming were those at 4 min after the start of rewarming the skin (TBAT, expired CO2, HR, and Tskin) or the averages during the 4th min after the start of the skin rewarming (BAT SNA, MAP, Trec, and Tbrain). Values of BAT SNA are expressed as percentage of the mean value before cooling.
P < 0.05,
P < 0.01, and
P < 0.001 compared with the values before cooling;
P < 0.05,
P < 0.01, and
P < 0.001 compared with the values at the end of cooling (Bonferroni multiple comparisons test following a repeated measures ANOVA).