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. Author manuscript; available in PMC: 2009 Jun 1.
Published in final edited form as: Mol Cancer Res. 2008 Jun;6(6):929–936. doi: 10.1158/1541-7786.MCR-07-2189

Table 1.

Significance of selected stem/progenitor subpopulations

Stem/progenitor subpopulation Significance
CD34+38− Primitive CD34+ cell; important in late engraftment & enriched in cord blood
CD34+45+ Human hematopoietic stem cell
CD34−45+ Human myeloid progenitor cell
Sca1+Gr1+ Hematopoietic stem cell of mouse BM (also displaying evidence of myeloid differentiation)
Sca1−Gr1+ Expresses Gr -1 (Ly6G) myeloid differentiation differentiation antigen, found on bone marrow monocytes and granulocytes as well as peripheral neutrophils
VEGFR2+ (Flk1+) (vascular endothelial growth factor receptor 2) consensus marker for EPCs (also important in multiple angiogenic processes)
VEGFR1+ (Flt1 (Flt1+) (vascular endothelial growth factor receptor 1) Expressed by a subpopulation of hematopoietic stem cells; receptor for VEGF and Placental Growth Factor
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