Table 2. Univariate relapse free log-rank analysis.

Variable	HR (95% CI)	P-value (original set)	P-value permutation (n=10 000)
Epithelial expression (negative vs positive)	8.76 (2.41–31.83)	0.001	0.0001
Epithelial expression (continuous)	10.79 (2.50–46.56)	0.001	0.0003
pT stage (pT2 vs pT1)	0.55 (0.17–1.80)	0.324	0.377
Age (years)	0.97 (0.93–1.02)	0.330	0.310
SBR grade
II vs I	1.07 (0.28–4.14)	0.923	1.000
III vs I	1.62 (0.33–8.07)	0.573	0.586
Hormone therapy (yes vs no)	0.67 (0.18–2.47)	0.550	0.562
Her2 (3+ vs 0, 1, 2+)	2.74 (0.35–21.21)	0.334	0.395
PR (negative vs positive)	2.39 (0.73–7.79)	0.148	0.062
ER (negative vs positive)	—	NC*	NC*

ER=oestrogen receptor; HR=hazard ratio; PR=progesterone receptor.

^*NC, not calculable.