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. 2008 Jun 12;9:284. doi: 10.1186/1471-2164-9-284

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Copyright © 2008 Bechtel et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Distribution of strong local SS with respect to folding energy in mRNAs and genomic sequences. Number of structures was measured within 1 kcal/mol intervals and normalized by 1,000 nucleotides of analyzed sequences. (A) 5'-UTRs (blue) and two independent SRI-generated sequences (gray); (B) 3'-UTRs (yellow) and two independent SRI-generated sequences (gray); (C) introns (green) and two independent SRI-generated sequences (gray); (D) intergenic regions from chromosome 17 (red) and two independent SRI-generated sequences (gray); (E) CDS (burgundy) and two independent CDS-generated sequences (gray); (F) 3'-UTRs (yellow), random MRI-generated counterpart sequences (black), and random SRI-generated counterpart sequences (gray).