Table 1.

Average (Av.) relative ncRNA expression levels after RNAi depletion of individual protein components of snoRNPs.

		ncRNA class
Protein depleted		C/D snoRNAs		H/ACA snoRNAs		snRNAs		Sm Y RNAs		sbRNAs		Other ncRNAsa
		Av.	P	Av.	P	Av.	P	Av.	P	Av.	P	Av.	P
C/D box snoRNPs	Snu13	0.24	1.6 × 10-6	0.83	2.9 × 10-3	0.99	1.9 × 10-2	0.48	4.4 × 10-1	5.44	6.6 × 10-3	0.52	4.9 × 10-1
	Nop1	0.55	1.2 × 10-5	1.31	1.6 × 10-3	1.07	5.1 × 10-2	0.68	7.7 × 10-1	5.70	1.3 × 10-1	0.84	4.9 × 10-1
	Nop58	0.33	1.4 × 10-6	1.03	1.2 × 10-4	0.76	1.5 × 10-2	0.38	3.5 × 10-1	5.39	1.3 × 10-1	0.53	3.9 × 10-2
	Nop56	0.93	3.7 × 10-2	0.96	8.2 × 10-1	1.03	2.8 × 10-1	0.96	8.3 × 10-1	1.98	4.1 × 10-4	0.99	8.9 × 10-1
	Gar1	0.89	7.3 × 10-2	0.93	7.1 × 10-1	0.93	8.2 × 10-1	0.81	8.8 × 10-2	5.61	2.7 × 10-7	0.91	9.0 × 10-1
H/ACA Box snoRNPs	Cbf-5	0.92	7.8 × 10-2	0.68	1.2 × 10-5	1.01	9.3 × 10-3	0.76	3.6 × 10-1	1.28	8.4 × 10-3	0.90	3.8 × 10-1
	Nhp2	0.88	1.4 × 10-2	0.41	7.4 × 10-9	1.09	3.0 × 10-3	1.07	9.6 × 10-2	3.54	6.3 × 10-3	0.80	3.7 × 10-1
	Nop10	0.87	3.2 × 10-3	0.19	1.3 × 10-8	0.68	6.0 × 10-2	0.97	1.2 × 10-1	3.42	5.8 × 10-3	0.93	5.7 × 10-2

Relative expression was calculated as treated sample (RNAi; Cy5)/control (Cy3). Statistical significance was calculated using a two tailed student t-test.

^a "Other ncRNAs" include SRP RNA, RNase P RNA and unclassified ncRNAs.