. 2008 Jun 30;105(27):9355–9360. doi: 10.1073/pnas.0801294105

Table 1.

Peak I_Na density, the percentage of late normalized to peak, and sodium channel kinetics from n experiments averaged and reported as mean ± SEM

Samples	Peak I_Na		Activation			Inactivation			I_NaL
Samples	pA/pF	n	V_1/2, mV	K	n	V_1/2, mV	K	n	%	n
SCN5A	−233 ± 38	9	−40 ± 2	4	9	−77 ± 2	5	9	0.34 ± 0.09	5
SNTA-WT	−238 ± 33	10	−44 ± 2	4	7	−76 ± 2	5	9	0.16 ± 0.04	9
SNTA-A390V	−393 ± 39^*	16	−41 ± 2	4	9	−69 ± 2^*	6	15	0.62 ± 0.29	18
SNTA-A390V + l-NMMA	−336 ± 37^*	6	−44 ± 2	4	6	−75 ± 2	5	6	0.15 ± 0.04	4
SNTA-WT + NOR3	−400 ± 67^*	12	−47 ± 1	4	11	−78 ± 1	5	12	0.31 ± 0.07	12
SNTA-WT + GSNO	−427 ± 151^*	5	−39 ± 2	4	3	−77 ± 3	5	5	0.54 ± 0.22^*	5

The parameter fits were obtained from individual experiments with Boltzmann or exponential fits (see Materials and Methods).

*P < 0.05 versus SNTA-WT.