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. 2008 Jun 30;2008:814815. doi: 10.1155/2008/814815

Figure 5.

Figure 5

Induction of LTP in the horizontal pathway required an increase in postsynaptic calcium. (a) Normalized scaled amplitude of peak EPSCs evoked by test pulses in a layer II cell loaded with 10 mM BAPTA is plotted against time. HFS was routinely applied about 15 minutes after formation of whole-cell mode to ensure adequate BAPTA diffusion. The inset shows two traces reflecting averaged EPSCs at baseline (pre-HFS) and at 30 minutes post-HFS. (b) Average normalized scaled amplitude of peak EPSCs across 5 BAPTA-loaded cells. HFS at time zero induced only short-term (PTP) but not long-term potentiation. The value at 30 minutes post-HFS (1.008 ± 0.068) was not significantly different from baseline (P > .05).