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Analysis of Gal-1, Gal-2, and Gal-3 interactions with glycans utilizing SPR
| Lactose (Kd) | LacNAc-LacNAc (Kd) | LacNAc-LacNAc-LacNAc (Kd) | |
|---|---|---|---|
| μm | μm | μm | |
| Gal-1 S1a | 13.7 | 15.1 | 16.7 |
| Gal-1 S2 | 14.4 | 16.9 | 19.2 |
| Gal-1 S3 | 9.0 | 11.0 | 12.1 |
| Gal-2 S1 | 24.9 | 60.5 | 62.6 |
| Gal-2 S2 | 28.3 | 77.6 | 66.7 |
| Gal-2 S3 | 32.3 | 58.4 | 54.5 |
| Gal-3 S1 | 53.5 | 8.4 | 2.7 |
| Gal-3 S2 | 60.7 | 9.5 | 3.2 |
| Gal-3 S3 | 51.4 | 9.5 | 3.9 |
S1, S2 and S3 represent separate analyses of each respective galectin under identical conditions.
