TABLE 2.
Fasting plasma biochemistry in AdHSL- and AdATGL-infected mice Comparisons between two groups of animals (n = 4–9/group) were made using the Mann-Whitney U test for AST and ALT and Student's t test for all other parameters. p values were derived from comparisons made against AdGFP-infected animals.
| Strain | Diet | Sex | AdGFP | AdHSL | AdATGL | |
|---|---|---|---|---|---|---|
| AST (IU/ml) | FVB-ob/ob | Chow | F | 99 ± 44 | 61 ± 9 | 96 ± 35 |
| FVB-ob/ob | Chow | M | 66 ± 9 | 42 ± 2a | ||
| B6 | WTD | M | 39 ± 23 | 32 ± 16 | ||
| ALT (IU/ml) | FVB-ob/ob | Chow | F | 705 ± 579 | 269 ± 129 | 454 ± 362 |
| FVB-ob/ob | Chow | M | 813 ± 484 | 183 ± 88a | ||
| B6 | WTD | M | 210 ± 86 | 172 ± 73 | ||
| FFA (mmol/liter) | FVB-ob/ob | Chow | F | 1.04 ± 0.11 | 0.88 ± 0.29 | 1.26 ± 0.46 |
| FVB-ob/ob | Chow | M | 1.12 ± 0.24 | 1.00 ± 0.39 | ||
| B6 | WTD | M | 0.49 ± 0.12 | 0.50 ± 0.09 | ||
| TG (mg/dl) | FVB-ob/ob | Chow | F | 128 ± 27 | 151 ± 37 | 158 ± 70 |
| FVB-ob/ob | Chow | M | 148 ± 34 | 166 ± 27 | ||
| B6 | WTD | M | 41 ± 13 | 42 ± 16 | ||
| TC (mg/dl) | FVB-ob/ob | Chow | F | 133 ± 21 | 83 ± 8a | 125 ± 24 |
| FVB-ob/ob | Chow | M | 131 ± 17 | 121 ± 40 | ||
| B6 | WTD | M | 225 ± 28 | 213 ± 35 | ||
| 3-HB (μmol/liter) | FVB-ob/ob | Chow | F | 223 ± 91 | 351 ± 81 | 331 ± 265 |
| FVB-ob/ob | Chow | M | 143 ± 44 | 724 ± 581 | ||
| B6 | WTD | M | 99 ± 54 | 67 ± 64 | ||
| Glucose (mg/dl) | FVB-ob/ob | Chow | F | 144 ± 23 | 313 ± 141 | 203 ± 80 |
| FVB-ob/ob | Chow | M | 439 ± 141 | 401 ± 211 | ||
| B6 | WTD | M | 204 ± 34 | 216 ± 25 | ||
| Insulin (ng/ml) | FVB-ob/ob | Chow | F | 17.6 ± 14.7 | 29.3 ± 13.3 | 14.6 ± 10.4 |
| FVB-ob/ob | Chow | M | 7.1 ± 4.5 | 8.0 ± 3.9 | ||
| B6 | WTD | M | 1.3 ± 0.5 | 1.3 ± 0.5 |
a
Values shown are p < 0.05