FIGURE 2.

Secretion of SDF-1 by a monolayer of hMSCs and hMSC spheroids. Concentrations of SDF-1 were measured in medium conditioned by a monolayer of hMSCs and one- (SPH1), two- (SPH2), and three- (SPH3) day-old hMSC spheroids using enzyme-linked immunosorbent assay and normalized to the total number of cells. Mean values of relative secretion ± S.D. of SDF-1 by hMSCs (n = 4), SHP1 (n = 8), SPH2 (n = 4), and SPH3 (n = 4) are shown. Statistically significant changes in comparison with hMSCs are denoted by asterisks (^*, t-test, p value <0.05).