Table 2.
Median CD64 and CD163 MFI and indexes (i) for neutrophils and monocytes with 95% confidence interval (CI) in critically ill neonates and children at the time of suspected sepsis (day 0) and 24 hours later (day 1).
| Day 0 | Day 1 | |||||
|---|---|---|---|---|---|---|
| SIRS with sepsis | SIRS | P | SIRS with sepsis | SIRS | P | |
| Neutrophils | ||||||
| CD64fMFI | 83 (66–108) | 44 (36–56) | .0000* | 100 (75–162) | 47 (32–54) | .0000* |
| CD64i | 2.65 (2.02–4.03) | 1.3 (1.06–1.78) | .0000* | 3.36 (2.27–4.68) | 1.47 (1.07–1.78) | .0000* |
| CD163MFI | 65 (50–85) | 47 (44–64) | .0463* | 80.5 (57–115) | 50.5 (40.2–84.8) | .0056* |
| CD163i | 456 (423–548) | 447 (381–491) | .2250 | 527 (486–621) | 462 (426–528) | .0495* |
|
| ||||||
| Monocytes | ||||||
| CD64MFI | 251 (231–294) | 168 (149–212) | .0000* | 307 (257–354) | 195 (159–243) | .0001* |
| CD64i | 9.36 (7.94–11.2) | 6.69 (5.6–7.28) | .0001* | 11 (8.39–13.4) | 7.41 (6.43–8.22) | .0003* |
| CD163MFI | 2350 (1674–3942) | 1451 (1234–1637) | .0063* | 3281 (2369–4093) | 2483 (1927–2937) | .0439* |
| CD163i | 20080 (9330–27352) | 9460 (7708–14893) | .0836 | 21136 (13636–32551) | 20142 (15926–25366) | .9598 |
*statistically significant differences, Unpaired Mann-Whitney test.