Figure 1.
The predicted reduction in strength caused by a reduction in bone mineral content or bone mineral density (as would be measured by dual-energy x-ray absorptiometry) is shown 1) a hypothetical case where changes in bone mineral content are caused entirely by changes in volume fraction (dark blue region) and 2) a hypothetical case where changes in bone mineral content are caused entirely by reductions in tissue degree of mineralization (light orange region). The overlapping regions are based on the 95% confidence interval of the regression model reported by Hernandez and colleagues[41].