Table 1.
Patients' Characteristics
| Modafinil treated group (n = 32) | Placebo treated group (n = 21) | P | |
|---|---|---|---|
| M : F | 16 : 16 | 10 : 12 | 0.469 |
| Mean age, yr | 31.4 ± 12.3 | 29.1 ± 9.9 | 0.490 |
| EDS onset age, yr | 17.9 ± 4.9 | 17.6 ± 5.1 | 0.814 |
| Cataplexy onset age, yr | 20.5 ± 5.5 | 19.6 ± 5.1 | 0.533 |
| Mean ESS | 17.2 ± 3.5 | 16.0 ± 3.9 | 0.252 |
| Mean SSS | 4.3 ± 1.9 | 4.4 ± 2.0 | 0.762 |
| HH/SP, number | 23/19 | 17/15 | 0.754/0.842 |
| Overnight polysomnography | |||
| Mean sleep latency, min | 7.6 ± 3.8 | 6.4 ± 3.5 | 0.264 |
| Mean REM sleep latency, min | 50.0 ± 46.8 | 60.7 ± 44.1 | 0.408 |
| Mean AHI, per hour | 1.7 ± 1.6 | 1.6 ± 1.7 | 0.882 |
| Mean arousal index, per hour | 13.7 ± 5.5 | 11.5 ± 4.5 | 0.114 |
| Multiple Sleep Latency Test | |||
| Mean sleep latency, min | 3.8 ± 2.9 | 4.6± 2.8 | 0.299 |
| Sleep-onset REM periods, number | 3.7 ± 1.3 | 3.7 ±1.2 | 0.975 |
| Mean REM sleep latency, min | 2.6 ± 2.3 | 2.9 ± 2.6 | 0.675 |
ESS, Epworth Sleepiness Scale; SSS, Stanford Sleepiness Scale; HH, hypnagogic hallucination; SP, sleep paralysis; REM, rapid eye movement; Independent t-test, P < 0.05, #Chi-square test, only in case of M:F and HH/SP, number, P < 0.05.