Table 1.

Clinical features of cohort

Gender F : M	1.2 : 1
Age at symptom onset (years)	37 (8–69)
Disease Duration
Symptom onset to biopsy (weeks)	7.1 (3.7, 28.6)
Symptom onset to last F/U (years)	3.9 (2.0, 9.0)
Clinical course prior to biopsy (%)
First neurological event	61
Relapsing–remitting	29
Secondary progressive	1
Primary progressive	2
Progressive-relapsing	1
Uncertain	6
Clinical course at last F/U (%)
Monophasic	24
Relapsing–remitting	51
Secondary progressive	11
Primary progressive	1
Progressive-relapsing	3
Uncertain	9
Diagnosis at last F/U (%)
Multiple sclerosis	70
Probable multiple sclerosis	9
Isolated demyelinating syndrome	14
Unknown	7
EDSS
At time of index attack	3.5 (3.0, 4.5)
At last follow-up	3.0 (1.5, 4.0)

Note: values in parentheses are either minimum – maximum or lower quartile, upper quartile.