Figure 6.
NRG-1 increases survival after OGD but not glutamate exposure. B-35 cells were subjected to 90 minutes of OGD 22.5 hours of reoxygenation. NRG-1 treatment resulted in a two-fold increase in cell viability (A). When B-35 cells were incubated with 50 µM glutamate, NRG-1 did not protect neurons from glutamate excitotoxicity. Values are represented as means ± SEM; * denotes difference from control, # denotes difference from OGD (n = 5; p<0.05).