Table 1.
Frequency (MHz) | Pressure amplitude (MPa)* | N locations (threshold) | Reference(s) | N locations (histology) | Reference |
---|---|---|---|---|---|
0.26 | 0.1 – 0.6 | 54 | 1, 2 | 7 | 2 |
0.69 | 0.4 – 1.5 | 60 | 3, 4 | 8 | 4 |
1.50 | 0.4 – 2.6 | 119** | 5 | -- | -- |
1.63 | 0.7 – 4.7 | 139*** | 6, 7 | 13**** | 7 |
2.04 | 0.3 – 2.3 | 40 | N/A | 8 | N/A |
Estimates in the brain;
30s sonications in rats, 3T MRI; all other data acquired in rabbits with 20s sonications, 1.5T MRI;
100 ms bursts; all other data used 10 ms bursts;
Animals sacrificed 72h after sonication; all other cases, animals were sacrificed 4h after sonication