Table 1.

Estimated relative mutation rates for pairs of reciprocal substitutions^a

Transition/Transversion	CpG	Substitution pair	RMR
Transversion	nonCpGb	C:G > A:T	2.0
Transversion	nonCpGb	C:G > G:C	2.0
Transition	nonCpG	C:G > T:A	7.3
Transversion	CpG	C:G > A:T	16.0
Transversion	CpG	C:G > G:C	16.0
Transition	CpG	C:G > T:A	96.7
Transversion	nonCpG	A:T > C:G	2.2
Transition	nonCpG	A:T > G:C	7.3
Transversion	nonCpG	A:T > T:A	1.8

^aOriginal data and computing of relative mutation rates can be found in Additional file 1.

^bRelative mutation rate is one per transversion C > A or G > T giving 2 for the C:G > A:T pair