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. 2008 Jul 7;205(7):1551–1557. doi: 10.1084/jem.20080218

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© 2008 Ma et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 2. — Deficiency of RORγt mRNA in HIES patients. (A) RORγt mRNA expression in CD4⁺ cells activated for 2 d with CD3/CD28/IL-2 in five HIES patients and five normal controls. (B) RORγt mRNA expression after 2 d of culture is proportional to the number of Th17 cells as determined by intracellular cytokine expression after 4–5 d.